Y. T. RAJESH BABU*, PRATHAMANJALI SATAPATHY, B. ASHOK RAMA RAJU, J. RAMALAKSHMANA AND S. B. PADAL
Department of Botany, Andhra University, Visakhapatnam-530 003 (Andhra Pradesh), India *(e-mail: baburajesh0999@gmail.com; Mobile: 63008 84860, 90527 96457)
(Received: December 1, 2023; Accepted: January 11, 2024)
ABSTRACT
The present study aimed at analyzing the phytochemical components with a GC-MS approach and to figure out the antimicrobial effectiveness of plant extracts against pathogenic bacterial strains (Salmonella enterica, Pseudomonas sps, Streptococcus mutans, Staphylococcus aureus) and pathogenic fungi (Candida albicans, Aspergillus flavus, Aspergillus niger and Rhizopus oryzae). A qualitative phytochemical evaluation of the entire plant indicated the presence of alkaloids, phenols, tannins, flavonoids, terpenoids, glycosides and so on. The qualitative phytochemical data were further validated by the GC-MS analysis of the entire plant crude extract. Thirty-two compounds, most significantly 1,4,7,-Cycloundecatriene, 1,5,9,9- tetramethyl-, Z,Z,Z, -Asarone, Phthalic acid, di(2-propylpentyl) ester and Bis (2-ethylhexyl) isophthalate were determined from the methanolic extract in the GC-MS evaluation. These chemicals had a variety of medicinal and antimicrobial properties. Furthermore, more research on P. tetraphylla is required due to its broad spectrum of beneficial pharmacological properties as a potential antimicrobial agent.
Key words: Phytochemical components, GC-MS approach, antimicrobial effectiveness, pharmacological activities