APOORVA RANA, ANUSHKA CHATTERJEE, MANISH GOYAL, GAJENDRA KUMAR ASERI, SANDEEP K. SHRIVASTAVA AND NEERAJ KHARE*
Institute of Allied Medical Science and Technology, NIMS University, Jaipur-303 121 (Rajasthan), India
(e-mail: neerajsnkhare@gmail.com; Mobile: 70735 92400)
(Received: December 15, 2022; Accepted: February 8, 2024)
ABSTRACT
The methicillin resistant Staphylococcus aureus (MRSA) is considered to be amongst the most prevalent microorganisms contributing towards the outspread of antimicrobial drug resistance. To overcome this threat, there is an urgent requirement of some effective antimicrobial agents. The present study was planned to screen the anti-MRSA potentials of the methanolic and ethanolic extracts of leaves and roots of Tephrosia purpurea. The ethanolic roots of Tephrosia were shown to possess the best anti-MRSA potentials (Activity Index = 0.56) amongst the extracts tested. The results demonstrated that Tephrosia extracts should be further analyzed to identify the bioactive phytoconstituents and the possible mechanism responsible for plant’s anti-MRSA potentials.
Key words: MRSA, medicinal plants, Tephrosia purpurea, activity index